Study finds coffee may help battle colon cancer

By Michael Lasalandra
Copyright 1999 Boston Herald
January 22, 1999



Maybe you should skip the bran muffin and have an extra cup of coffee instead.

Now that it has been shown that eating a high-fiber diet does not protect against colon cancer, some are looking to java as a way to prevent the deadly disease.

Dr. Edward Giovannucci of the Harvard School of Public Health published a study last year suggesting that the risk of colorectal cancer drops 24 percent among those who drink four or more cups of coffee a day.

But before you go out and invest in a Starbucks franchise, take note. Giovannucci says the study is far from conclusive.

"I wouldn't tell people to go out and start drinking coffee, although there isn't much harm in it," he said.

Experts say the best ways to prevent colorectal cancer are still taking vitamins, staying in shape, taking an aspirin a day, avoiding red meat and getting regular screenings after age 50.

Giovannucci's paper, which reviewed all the literature on the subject of coffee and colorectal cancer, appeared in the American Journal of Epidemiology. But he downplayed its importance.

"I'm not sure the 24 percent reduction in risk is a cause and effect association," he said.

"It would be important if it is real, but it is hard to say in an epidemiological study that there isn't a bias or other factor that is accounting for this."

Giovannucci said the results were interesting enough to warrant further study, which is what Vanderbilt University in Nashville is planning to do. Vanderbilt is scheduled to open its Institute for Coffee Studies within the next six months, thanks to $6 million in funding from trade groups in leading coffee-producing nations.

"We're going to help people get over the idea that coffee is caffeine," said Vanderbilt's Peter Martin. "Caffeine actually is a very small component of coffee. There are many other components that aren't well understood."

Some studies have suggested coffee can help relieve depression, treat alcoholism and prevent colorectal cancer. The institute's mission is to understand why.

Although it may not reduce the risk of colon cancer, eating lots of fruits, vegetables and cereals has been shown to help prevent diverticulitis, high blood pressure and heart disease. But preventing colorectal cancer may require more technology-oriented strategies.

Dr. Francis Farraye, a gastroenterologist at Harvard Vanguard Medical Associates, says those over 50 should discuss colorectal screening with their doctors.

There are several methods, including an annual stool test; a test in which a scope is inserted into the lower third of the colon, once every five years; a barium enema, done every five to 10 years; or a more invasive test in which a scope is inserted into the entire colon, usually once every decade.

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